Search results for "SELECTIVE IONIZATION"

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Very high specific activity erbium 169Er production for potential receptor-targeted radiotherapy

2019

Erbium 169Er is one of the most interesting radiolanthanides for new potential receptor-targeted β− therapy applications due to its low energy β− emissions, very low intensity ɣ rays and the possibility to use 68Ga or 44Sc as companion for diagnostic in a theranostics approach. Currently it can be produced in reactors through the neutron activation of highly enriched 168Er. The low specific activity of the produced carrier-added 169Er is limiting its use for receptor-targeted therapy. Nonetheless it is used for radiosynoviorthesis of small joints. The aim of this work is to develop a new large-scale production method for the supply of very high specific activity 169Er. Highly enriched 168Er…

Nuclear and High Energy PhysicsHIGH SPECIFIC ACTIVITIESMaterials scienceTargeted Radiotherapychemistry.chemical_elementLASER IONIZATION7. Clean energy030218 nuclear medicine & medical imaginglaw.inventionErbium03 medical and health sciences0302 clinical medicinePRECLINICAL STUDIESlaw[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Production (economics)HIGH SPECIFIC ACTIVITYIrradiationInstrumentationComputingMilieux_MISCELLANEOUSATOM LASERSRadiochemistrySELECTIVE IONIZATIONNuclear reactorERBIUMRESONANT LASER IONIZATIONLARGE SCALE PRODUCTIONSchemistryHigh specific activityER-169030220 oncology & carcinogenesisSEPARATION EFFICIENCYTARGETED RADIOTHERAPYIONIZATIONSpecific activityRECEPTOR-TARGETED THERAPYNeutron activationNUCLEAR REACTORSNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
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